Volume 96 Issue 7 | p. 10 | News of The Week
Issue Date: February 12, 2018 | Web Date: February 7, 2018

Drug development success rates are higher than previously reported

A study of nearly 186,000 clinical trials found that 13.8% of compounds make it from Phase I to approval
Department: Business
Keywords: Drug discovery, clinical trials, drug success, drug failure, drug approval

The largest study yet assessing the success rates of clinical trials for drugs has yielded more optimistic data than previous studies.

Andrew W. Lo and colleagues at the MIT Laboratory for Financial Engineering used an automated algorithm to draw data from nearly 186,000 unique trials of over 21,000 compounds, from January 2000 through October 2015. The team found that 13.8% of drug programs make it from Phase I to approval, a higher figure than the . . .

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